Sunday, February 5, 2012

Antioxidants and Free Radicals


Until the beginning of the 20th century, no one knew that free radicals can be tangible and work freely. Our scientific understanding of the relationship of free radicals with antioxidants appear on the new three to four decades. The chemists in the 19th century originally used the term free radicals to a group of atoms that form a molecule. At that time, scientists do not believe that free radicals can be in a free state.

Free radicals are molecules missing an electron, so that the molecule becomes unstable and is always trying to take electrons from other molecules or cells. Free radicals can be generated from the metabolism of the body and external factors such as cigarette smoke, the result of ultra violet radiation, chemicals in food and other pollutants that cause damage to cells, proteins and DNA by altering the chemical composition of cells in the body.
Actually, free radicals are important for the health and normal body function in a fight inflammation, kill bacteria, and control of vascular smooth muscle tone and organs in our body. Free radicals are key to his safe and effective in our body when not in excessive amounts or in a state of balance, but the problem is a balancing mechanism of our body is very fragile so often out of line, giving rise to disease. When our bodies are filled with excessive free radical is an unstable molecule that resides in our bodies transform into molecular predators. They began to move wildly and attacking the body's healthy or unhealthy, causing disease.
For example, the human body to produce Glutathione,
one of a very powerful antioxidant, but the body requires vitamin C intake of high doses of 1,000 mg to trigger the body to produce glutathione. The balance between antioxidants and free radicals is the key factor preventing oxidative stress and chronic diseases that result.

 
There are some diseases that have been investigated and allegedly related to free radical activity that includes more than 50 disorders such as stroke, asthma, pancreatitis, inflammatory bowel diseases, chronic blockage of blood vessels in heart disease, Parkinson's, Sel Sickle leukemia, rheumatoid arthritis, brain bleeding and high blood pressure, and even AIDS.
To fix this situation our bodies form a free radical fighter, known as an endogenous antioxidant. Endogenous antioxidants neutralize free radicals will be excessive so as not to damage the body. Endogenous antioxidant was stated by American scientists on tahun1968 by JM Mc Cord and I. Fridovich who discovered a natural antioxidant enzymes in the human body that is currently superoksid dismutase SOD shortened. Only a short time after the theory is presented, then found a natural antioxidant enzymes such as Glutathione peroxidase, catalase, ready to neutralize the excessive free radicals in order to remain balanced. Currently natural antioxidant enzymes have been able to check the levels in the body in the laboratory. While we eat antioxidant from outside through food or through food supplements to help your body fight excess free radicals, we call exogenous antioxidants.
By Phyllis A Balch, James F. & Cnc Balch, MD in his book Prescription for Nutritional Healing is an exogenous antioxidants can be included in this are: Alpha lipoic acid (ALA), Bilberry (Vaccinium myrtillus), Burdock (Artium lappa), carotenoids, coenzyme Q 10, Curcumin (tumeric), Flavonoids , Garlic, Ginkgo biloba, Glutathione, Grape seed extract, Green tea, melatonin, Mettthionine, N-Acetylcysteine ​​(NAC), HDAC inhibitors Adenine dinucleotide (NADH), Oligomeric proanthocyanidins (OPCs), Pycnogenol, Selenium, Silymarin, Vitamin A, Vitamin C , Vitamin E, Zinc.
Unfortunately, the protection system from within and from outside the body is often inadequate because too many free radicals are formed as air pollution, cigarette smoke, ultraviolet light produced by sunlight, pesticides and other contaminants in our food, even because of excessive exercise.
It seems that wherever we move the various compounds and circumstances continue to haunt us with a variety of free radical-induced our own.

There are 4 steps that can be done according to Dr. Kenneth H. Cooper who initiated Preventive medicine to fight the harmful free radicals in our bodies, namely:
1. Low-intensity exercise
2. Combining several antioxidants every day
3. Set the proper diet and cooking the antioxidants in food is not broken
4. Lifestyle free from free radicals
 
It is a difficult task to completely eliminate the free radicals that are very much present, but at least by knowing these free radicals, we can minimize the exposure so that we can make plans for life-long defense against the threat of rebel molecules.

Source : Dr.Albert GO Sumampouw / www.medikaholistik.com

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